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Recent Citations
Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1. Son Y, Kenny TC et al. Nature. 2024 May 16;629(8012):710–716.
Structural and molecular basis of choline uptake into the brain by FLVCR2. Cater RJ, Mukherjee D et al. Nature. 2024 May 16;629(8012):704–709.
Promiscuous G-protein activation by the calcium-sensing receptor. Zuo H, Park J et al. Nature. 2024 May 9;629(8011):481–488.
Structural insights into vesicular monoamine storage and drug interactions. Ye J, Chen H et al. Nature. 2024 May 2;629(8010):235–243.
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules. Dodd DO, Mechaussier S et al. Science. 2024 Apr 26;384(6694):eadf5489.
Previously featured citations...Chimera Search
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October 30-31, 2023
Planned downtime: The Chimera and ChimeraX websites and associated web services will be unavailable Oct 30 8am PDT – Oct 31 11:59pm PDT.
April 19, 2023
Chimera production release 1.17.1 is now available, fixing an issue with 1.17 for Windows and Linux. See the release notes for details.
April 13, 2023
Chimera production release 1.17 is now available. Updating is required to keep using the tools that run Blast Protein, Modeller, and multiple sequence alignment with Clustal Omega or MUSCLE, as these will soon stop working in older versions. See the release notes for details.
Previous news...Upcoming Events
UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.
We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).
Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.
Feature Highlight
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Interactive shadows (shadows that move as structures are moved) can be enabled in the Effects dialog or with the command set shadows. Click the image to show a small molecule rotating above a rectangular plane. This simple animation was made with the Chimera command script tumble.com. Interactive shadows also work with ribbons, surfaces, and other representations.
(More features...)Gallery Sample
Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.
See also the RBVI holiday card gallery.
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