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Recent Citations
Hierarchical design of pseudosymmetric protein nanocages. Dowling QM, Park YJ et al. Nature. 2025 Feb 13;637(8050):553–561.
Structure and assembly of the dystrophin glycoprotein complex. Wan L, Ge X et al. Nature. 2025 Jan 30;637(8048):1252–1260.
Structural basis for the conformational protection of nitrogenase from O2. Narehood SM, Cook BD et al. Nature. 2025 Jan 23;637(8047):991–997.
Molecular mechanism of IgE-mediated FcεRI activation. Chen M, Su Q, Shi Y. Nature. 2025 Jan 9;637(8045):453–460.
High-resolution cryo-EM using a common LaB6 120-keV electron microscope equipped with a sub-200-keV direct electron detector. Venugopal H, Mobbs J et al. Sci Adv. 2025 Jan 3;11(1):eadr0438.
Previously featured citations...Chimera Search
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December 25, 2024
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October 14, 2024
Planned downtime: The Chimera and ChimeraX websites, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable starting Monday, Oct 14 10 AM PDT, continuing throughout the week and potentially the weekend (Oct 14-20).
August 1, 2024
Planned downtime: The Chimera and ChimeraX websites, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable August 1, 3-6 pm PDT.
Previous news...Upcoming Events
UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.
We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).
Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.
Feature Highlight
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Interactive shadows (shadows that move as structures are moved) can be enabled in the Effects dialog or with the command set shadows. Click the image to show a small molecule rotating above a rectangular plane. This simple animation was made with the Chimera command script tumble.com. Interactive shadows also work with ribbons, surfaces, and other representations.
(More features...)Gallery Sample
BILD format was used in Chimera to annotate the barrel structure of green fluorescent protein with its centroid, major axis (red arrow), and an enclosing cylinder (shown with green hoops). The BILD file green.bild was generated with the python program green.py using the coordinates in green.pdb. Gallery entry courtesy of Mike Ess, Yeast Resource Center, University of Washington. (More samples...)
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