| Measure Volume and Area | Area/Volume from Web |
|---|---|
| does not require internet connectivity | uses the StrucTools server |
| calculates total surface area and surface-enclosed volume, not values per atom | calculates per-atom surface areas and volumes and assigns them as attributes |
| works on surfaces shown in Chimera: molecular surfaces (solvent-excluded), GRASP surfaces, and isosurfaces from Volume Viewer and Multiscale Models | works on molecular coordinates; computes solvent-excluded surfaces, solvent-accessible surfaces, and atomic Voronoi volumes, but these are not displayed in Chimera |
| depends on parameter settings on Chimera such as the VDW radii and probe radius used to calculate a molecular surface | uses the internal parameter settings of the StrucTools server, which cannot be adjusted from Chimera |